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Medical Microbiology
Unit Exam 2 - Immunology
SHORT ANSWER KEY
1. List the term that refers to a natural antibody against ABO blood
group antigens.
2. Give the term that refers to excess immunoglobulin light chains found
in the urine.
3. A 72 year-old male patient is treated with antibiotics following abdominal
surgery and develops anemia. Name the laboratory test that would be used
to determine if the anemia may be caused by an antibody.
4. Name a tyrosine kinase that is an important signaling intermediate in
the B cell lineage and is nonfunctional in one form of agammaglobulinemia.
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Bruton's tyrosine kinase or Btk
5. What is the name of the intracellular peptide that prevents antigenic
peptides from binding to class II molecules until fusion has occurred between
the class II vesicle and the endosome.
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Either invariant chain (Ii) or CLIP
6. Name a genetic mechanism for generating antigen receptor diversity in
B lymphocytes that is not seen in T lymphocytes.
7. Name a component of the class I pathway of antigen presentation that
sizes and transports antigenic peptides into the ER lumen.
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TAP or transporter of antigenic peptide
8. Name an autoantibody against IgG that is commonly found in the sera
of patients with autoimmune diseases.
9. List the most common primary immune deficiency in the U.S. today.
10. Name the theory of autoimmunity that proposes that antibodies to infectious
agents can cross-react with host tissue antigens.
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