MEDICAL PHYSIOLOGY Respiration Conference Quiz 5A November 13, 2001 1. A patient breathing air at KUMC has arterial PO2 70 mm Hg, arterial PCO2 27 mmHg. The alveolar-arterial PO2 difference is 44.6;mm Hg. This is (high, normal, low). 2. List the mechanism(s) of gas exchange (ventilation, diffusion, VA/Q match) which could have participated in producing the PaO2 value of the patient in question 1. Low VA/Q. Low diffusion capacity Vintilation is high, would tend to increase PO2. 3. The PaCO2 value in the patient in question 1 would tend to (increase, decrease, no change) blood pH. To bring pH back to the normal value, plasma HCO3 must (increase, decrease, remain unchanged) 4. A patient with COPD has elevated Hb concentration. This will result in higher (blood PO2, O2 saturation of Hb, blood O2 content) than what would exist if Hb had remained unchanged. 5. A patient with a vital capacity of 6 L exhales 3 L in the first second of a forced vital capacity maneuver. This indicates (increased, normal, decreased) airway resistance. Patient (FEV1) / (FVC) = 3 / 6 = 0.5 Normal = 0.75 MEDICAL PHYSIOLOGY Respiration Conference Quiz 5B November 12, 2001 1. A patient breathing air at KUMC has arterial PO2 70 mm Hg, arterial PCO2 48 mmHg. The alveolar -arterial PO2 difference is 19 mmHg. Alveolar ventilation is (high, normal, low) 2. List the mechanism(s) of gas exchange (ventilation, diffusion, VA/Q match) which could have participated in producing the PaO2 value of the patient in question 1. Low ventilation (high PaCO2). Low VA/Q (high A-a PO2). Low diffusion capacity (high A-a PO2). 3. The PaCO2 value in the patient in question 1 would tend to (increase, decrease, no change ) blood pH. To bring pH back to the normal value, plasma HCO3 must (increase, decrease, remain unchanged). 4. A patient with COPD has elevated Hb concentration. This will result in higher (blood PO2, O2 saturation of Hb, blood O2 content) than what would exist if Hb had remained unchanged. 5. A patient with elevated airway resistance has a vital capacity of 5 L. You would expect that the volume of air exhaled in the first second of a forced vital capacity would be approximately (3.5 -4.0 L, higher than 3.5-4.0 L, lower than 3.5-4.0 L)