Medical Biochemistry (BIOC 801)
Fall 2005
Molecular Genetics

Dr. J. Calvet, 6001B WHE, 588-7424, email: jcalvet@kumc.edu

Reading Assignment:

Nussbaum, R.L. et al. "Thompson & Thompson Genetics in Medicine," 6th edition (Revised Reprint), Saunders, 2004. Chapters 1- 6; Clinical Cases: Familial Hypercholesterolemia, Xeroderma Pigmentosum, Hemophilia, Thalassemia, I-Cell Disease, p. 215; Telomerase pp. 318-320.

Baynes, J. and Dominiczak, M.H. "Medical Biochemistry," (2nd edition) Mosby, 2004. Chapters 29-33.

Internet Resources:

Online Mendelian Inheritance in Man (http://www3.ncbi.nlm.nih.gov/entrez/query.fcgi?db=OMIM)

Class Sessions/Lectures:
      1.  DNA, Genes, Chromatin
      2.  DNA Replication, Mutation, Repair
      3.  RNA Structure and Transcription
      4.  Eukaryotic Transcriptional Regulation
      5.  Class Discussion - Genetic Diseases
      6.  RNA Processing
      7.  Protein Synthesis and the Genetic Code
      8.  Protein Synthesis and Protein Processing
      9.  Class Discussion - Genetic Diseases
      10. DNA Cloning and Isolating Genes

Molecular and Human Genetics
     Learning Objectives for Medical and Human Genetics
     Lectures - Fall 2005
     Lectures - Spring 2006
     Internet Research Assignment
     Health Careers Pathways Pre-Matriculation Program

  Medical Biochemistry